MetaRNA is a European research-training network, in which young researcher will do their PhD, and thereby will be excellently prepared for the future academic or industrial job market.
PhD students in the network will do exciting science at the interface between RNA biology and metabolism. We will develop RNA-based molecular sensors, with which we can probe cellular metabolism at the single cell level. Such capability will allow us to address important problems in diseases and biotechnology, where increasing evidence suggests that metabolic cell-to-cell heterogeneity is a key problem.Read more
Using latest insights and technology from the RNA field, we will develop molecular RNA-based sensors for metabolite. We will exploit computational design, robotics-assisted SELEX, MS-based biophysical aptamer characterization, …
We will exploit the developed molecular sensors to push metabolic research to the single cell level. Fundamental and cancer-relevant questions will be addressed also with approaches from systems biology.
We will harbor the potential of RNA-based sensor for biotechnological application. In collaboration with industry partners, we will open up new avenues for the development and improvement of cell factories.